Efetividade na prática de atividade física em crianças e adolescentes obesos e os níveis de interleucina-10 sérica

Abstract

Interleukin-10 (IL-10) plays an important role in immune function ininflammation and physical activity demonstrated shortly with thesynthesis of IL-10. We searched four databases up to February 20, 2023.Two reviewers screened the studies, collected data, assessed travel risk,and classified the evidence for each outcome across studiesindependently and in duplicate. The prespecified endpoints of interestwere physical activity; serum IL-10 levels; and Body Mass Index (BMI). Weonly included data from peer-reviewed articles in our primary analyses. Inour primary analysis, there was a positive trend between serum IL-10levels and body mass index; this result should be interpreted with caution.We identified 4 high-quality evidence that serum IL-10 levels and highphysical activity are in a considered direct relationship. Although the evidence available to date, from medium-quality observational studiesand clinical trials, can be seen as showing a trend toward the effectivenessof physical activity in obese children and adolescents and serum IL-10levels, this relationship has been shown to have an effect stimulating.Serum IL-10 levels about low body mass index are not based on solidevidence. We await results from ongoing studies to determine thisefficacy.